GURS Multi-Institutional Trials
In an effort to encourage collaboration and foster multi-institutional approaches to address research questions in our field of reconstructive/trauma urology, the multi-institutional trials committee (MITC) is accepting proposals for new multi-institutional studies. The goal for this effort is to encourage development of multi-institutional research and facilitate recruitment from institutions who want to participate in these studies.
The Process
- Submit study application, which can be found here
- Applications will be reviewed by the GURS-MITC in addition to independent reviewers with expertise in the study area/content
- If a study is approved, study and criteria for participation will be posted on the GURS-MIT webpage and interested centers may contact the primary study site for participation.
- Select studies will receive GURS monetary award and preferential publishing in the Gold Journal of Urology.
- Trials to be considered for the GURS monetary award will be reviewed biannually and are due on March 1st and September 1st.
Requirements
- Each study should be headed by one coordinating center whose principal investigator is responsible for the study design and proposal
- Must have clear data sharing plan
- Clear and clinically relevant hypothesis, feasible, and likely to impact clinical practice
The MITC is looking forward to your enthusiastic support and participation in these and future studies.
Current Trials
Duration of urethral catheter after bulbar urethroplasty
- Principle Investigator:
Jane Kurtzman, MD
University of Utah
jane.kurtzman@hsc.utah.edu - Co-Invesitgators:
Jeremy Myers, MD, University of Utah, Dr. Benjamin McCormick, MD, University of Utah - Study Title: Optimal Duration of Indwelling Urethral Foley Catheter Following Bulbar Urethroplasty: A Pragmatic Multi-Institutional Randomized Controlled Non-Inferiority Trial
- Study Aims: View PDF
Hypospadias & Mental Health Outcomes in Adults
Principle Investigator: Dan Wood, MD,
E-mail: dan.wood@childrenscolorado.org
University of Colorado
Co-investigator:
- Lindsay Hampson, MD MAS
- Annaliese Ionson, MD
- Mustafa Saeed
- Xinyuan Zhang, MD
- Hadley Wood, MD
- Judith Hagedorn, MD, MHS
Title: Hypospadias & Mental Health Outcomes in Adults
Specific Aims Page
Hypospadias is one of the most common congenital anomalies in males and typically requires surgical correction in early childhood. While much research has focused on surgical techniques and short-term functional outcomes, little is known about the long-term psychosocial consequences of hypospadias repair, particularly as patients transition into adulthood. Preliminary studies and anecdotal evidence suggest increased rates of depression, anxiety, and altered self-image in this population, but these outcomes have not been rigorously studied or compared to appropriate surgical controls. This lack of data limits our ability to counsel families effectively and to develop interventions aimed at supporting psychosocial well-being in patients undergoing genital surgery.
The long-term goal of this research is to improve the quality of life and mental health support available to individuals who undergo hypospadias repair in childhood. The overall objective of this study is to characterize and compare the mental health outcomes of adults who underwent hypospadias repair to those of adults who had non-genital childhood surgeries. Our central hypothesis is that individuals with a history of hypospadias repair will demonstrate higher rates of adverse mental health outcomes, such as anxiety, depression, and PTSD symptoms, compared to surgical controls. This hypothesis is based on prior qualitative studies and clinical experience suggesting long-term psychosocial impact in this population.
To test this hypothesis, we propose the following specific aims:
Aim 1: To assess the prevalence and severity of mental health symptoms (including depression, anxiety, PTSD symptoms, and quality of life) in adults who underwent hypospadias repair in childhood, using validated patient-reported outcome measures.
Aim 2: To compare these outcomes to those of a control group of adults who underwent other non-genital childhood surgeries (e.g., hernia repair), matched for age and demographic factors.
Aim 3: To identify clinical and demographic predictors of adverse mental health outcomes within the hypospadias group, such as number of surgeries, age at initial repair, and access to mental health resources.
The expected outcomes of this work include improved understanding of the long-term psychosocial effects of childhood hypospadias repair and identification of key risk factors. The impact of these findings will be to guide clinical counseling practices, inform mental health screening protocols, and support the development of targeted psychosocial interventions for this surgical population.
Impact of Time from Radiation on Artificial Urinary Sphincter Outcomes
- Principle Investigator: Madeline Cancian MD
Brown University
e-mail: madeline.cancian@brownphysicians.org
Brown University - Co-investigator: Lindsey Hartsell MD, Emory
- Title: Impact of time from radiation on artificial urinary sphincter outcomes
- Study Aims: View PDF